I've expecting some problems with my brand new Gene V:
I'm using the integrate SupremeFX III (ALC889 based) audio card for gaming and multimedia listening but randomly sounds disappear for about 1 second then re-appear.
On last time, also Realtek (not Creative MB2 software) control panel will continue to display a jack reinsertion (not true).
I've already updated it to lastest Realtek (not ASUS) version 188.8.131.5202.
No freeze or stuttering encour, mouse will free to move and video stream will continue to playback without problems.
CPU usage will every time on 3% - 7%, disabled all useless services on startup but no success.
This thing is very strange.
Using my USB sound card of Siberia v2 all works flawlessly but I want to use EAX and integrate audio of my motherboard.