you should do this in steps:
- first find out if your system is stable at stock. run prime95 for a few hours.
- then find out the min voltage your system needs to be stable at a defined CPU core clock.
- you can then start increasing CPU core clock until you find out it's not stable anymore.
- then you can go on increasing NB speed, HT speed, and finaly memory speed.
considering that your system is stable at stock, try this:
- on the Digi+ menu:
- cpu load line calibration: extreme
- cpu/nb load line calibration: extreme
- cpu over current protection: disabled
- nb over current protection: 130%
- cpu pwm phase control: extreme
- vrm over temp protection: disabled
- cpu voltage frequency: manual
- vrm fixed frequency mode: 550
- cpu pwm mode: extreme
on the extreme tweaker menu:
- ai overclock tuner: manual
- cpu level up: cancel
- cpu ratio: 20
- amd turbo core tech: disable
- cpu bus frequency: 200
- pcie frequency: auto
- memory frequency: place whatever you are using at stock
- cpu/nb frequency: 2000 ( for now

)
- HT link speed: 2000 ( for now ; ) )
- extreme OV: disabled
- cpu & nb voltage mode: manual
- cpu manual voltage: 1.52v
- nb manual voltage: 1.5v
- vdda votage: auto
- dram voltage: use whatever is at stock for now.
- vddr, vrefq, vrefca, vrefca on cpu: auto
- dram voltage switching freequncy: 2x
- dram over current protection: disabled
- nb voltage: 1.3
- nb ht voltage: 1.3
- nb 1.8v, vdd pcie, sb voltage: auto
- nv voltage switching freq: 2x
- nb 1.8v switching freq: 2x
- vdd pcie switching freq: 2x
leave you memory timmings at default.
don't worry about temperatures. if the cpu is running to hot it will throttle down or shut itself off prior to any damage.
it you can run your system stable with these settings, start lowering the cpu vcore until it is unstable. select the lowest vcore at wich your system was stable, put nb at 3000mhz and test for stability again, increasing nb voltage if it is unstable or decreasing if it is stable.
HT speed is not important, and memory speed on amd is also meaningless, so if can spare yourself the headache that it is to play with memory on the crosshair V.
good luck!