I have the strix i mini-itx and was having the same issues. I grabbed the "beta" set listed for your board, coincidentally, and that resolved all my issues. If you want the lastest drivers to function better click the settings icon top right corner ...
http://dlcdnet.asus.com/pub/ASUS/misc/audio/Realtek_Audio_Driver_Win7-81-10_V6017960.zip?_ga=1.263419851.699103937.1489564699Use this older version. It fixed all the issues for me.
JustinThyme wrote:The front panel audio is the supreme FX and 100% ASUS, nothing to do with Realtek although the drivers may be compiled into the same package. Its not going to sound the same because the drivers are not standard drivers. They have ...