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According to the manual: "The HYDRANODE pins are reserved for ASUS HYDRANODE devices."

The boot drive should be formatted with GPT, not MBR.

For others who might read this, after enabling and disabling PTT a few times on my Asus Z170-A with latest BIOS and ME Firmware, I'm starting to suspect PTT may have been hidden because it may be...

Is your boot drive using GPT? (GUID Partition Table)

You can try the official upgrade tool from Microsoft:
Windows 11 Installation Assistant
https://www.microsoft.com/en-us/software-download/windows11

Or, if you have an 8 GB USB stick, you can...

Run this app and see what it says: https://github.com/rcmaehl/WhyNotWin11

Win11 requires PTT/TPM 1.2 or 2.0, 8th generation CPU or newer, and Secure Boot.

PTT/TPM and secure boot might have to...

I don't have an answer, but is your boot drive using GUID Partition Table (GPT) (it should be using GPT not MBR)... Is your BIOS UEFI?

If you need Vulkan Runtimes, download them from here:
https://vulkan.lunarg.com/sdk/home
Click Latest Runtime/Zip

The ones included with Nvidia drivers are usually older anyway.

The BIOS should be UEFI, the boot drive should be using GPT, not MBR, if there is a CSM setting in the BIOS, it should be disabled (compatibility mode)

Windows 11 installs and runs just fine on unsupported CPU's, I tried it on my Asus Z170-A with the same CPU. Now I don't know if MS will later decide to block such CPU's, but if you know your Windows...

Read my thread here: https://www.win-raid.com/t9091f2705-Cannot-enable-Intel-PTT-TPM-at-ASUS-motherboard.html
It's a bit technical, so be careful. I had to do this to enable PTT/TPM 2.0 on my Asus...

BIOS should be UEFI
Drive should use GPT, not MBR
Disable CSM in BIOS, enable Secure Boot
Enable PTT/TPM in BIOS
Enable CPU Virtualization in BIOS (optional I think)

If you have an NVIDIA GPU, then you should install the DCH drivers directly from https://www.nvidia.com/Download/index.aspx

These renderers also work on Windows... https://github.com/doitsujin/dxvk/releases/tag/v1.9.2
The file dxvk-1.9.2.tar.gz can be extracted using 7-zip.

Just another thing to try, extract this twice and put the six dll's in the game folder:
DXVK https://github.com/doitsujin/dxvk
If not good, just delete the dll's

Try installing the latest Vulkan Runtime: https://vulkan.lunarg.com/sdk/home
And/or put the binary in the game folder (vulkan-1.dll)

In the start menu click Windows Security then click Device Security and see what it says. Do you have the latest BIOS update

Maybe you need to disable CSM in the BIOS

Check if you need to convert MBR to GPT:
https://www.howtogeek.com/245610/how-to-check-if-a-disk-uses-gpt-or-mbr-and-how-to-convert-between-the-two/
Secure Boot requires GPT

Your chipset does not support firmware TPM (Intel PTT), but your board has "TPM connector (20-1 pin TPM)" so you might be able to buy a Trusted Platform Module. The biggest problem here is the CPU,...

Did you load BIOS defaults? Did you check the manual for ethernet chip, wether it's Intel or Realtek etc.?

We had the same issue with the latest version of Windows 10 May 2021 on a Z590 Asus mobo, I was baffled it didn't have basic ethernet drivers, we used this Intel package:...

BIOS Settings, Monitor, CPU Fan Speed, Ignore... I have liquid cooling as well. You have to do this every time you reload BIOS defaults, or update your BIOS.

I checked your manual, your BIOS...