By "bad firmcode" I mean either a bug (design flaw, which may not have been apparent to ASUS until some special configuration/condition on your hardware triggered it) or corrupted data (a bad NVRAM flash session or whatever). The opposite of "good firmcode" which does what it's expected/supposed to do, properly, without any faults.
Maybe your VRM has bad contact with its heatsink? The TIM wasn't properly applied or has somehow leaked/cooked out?
The problem could be upstream. The PSU. Or even the AC power source. "Dirty" electrical power - lots of EMI noise/ripple, undervolts/overvolts approaching rated extremes, etc - passed onto your mainboard will place extra strain and stress on the VRMs, they'll have to work harder (and get hotter) to regulate power across the motherboard. Do you have any way of testing your AC power source and/or testing your PSU?
I don't have this mobo so I can't recommend any settings. But ASUS factory stock/default settings should work perfectly without causing any issues (other than perhaps being dull and not achieving maximal overclocking performance, lol). If not - and if your PSU is good - then you might have some sort of defective/damaged motherboard or processor component.
I note that the R5E is circa 2014-2015 ... if your mobo (and CPU) is already beyond 3-year warranty then don't be terribly surprised by hardware failure. Especially if you've sustained aggressive overclocks over the years.
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