Nothing monumental, can do the same with DIMM.2 slots and onboard M.2. This was done at launch of the platform with several different raid controllers, easy peasy. I’ve done this as far back as pentium machines where the board has no raid function. *The gripe with X299 always was trying to get non intel drives to boot from hyperX16 card that never worked and still won’t, only software raid and non bootable. Looking at your results you are still being bottlenecked and Q1 is lacking. *Two intel 900P drives in VROC gets me 5500MB/S sequential reads (nearly double yours) and 200MB/S Q1 reads (nearly 4X yours).**Put those same drives on a hyperX card and do software raid and you’ll get every bit of 7000 MB/S sequential but won’t be able to boot from it.*