From your past posts back in 2013, you are writing about an ASUS G75VW? The ASUS G75VW was developed back in 2011 and first came with Windows 7.
1. Has the laptop been upgraded to Windows 8, then 8.1, and then to 10?
2. Have you swapped out both the hard drives for SSDs? Hard drives have a spinning sound, SSDs are silent. Best performance improvement for this laptop.
3. Have you cleaned out and/or replaced both fans lately? The fans need to be cleaned every couple months or so. The fans do wear out and require replacement after a few years. G75VW fans are no longer sold by ASUS. New fans are still found on Amazon for less than $15 each. The laptop will have to be completely disassembled to replace the fans. Best left to technicians for best results.
4. How's the condition of the battery and/or the charging brick? The charging circuit on the motherboard have components that overtime, start to whine, high pitch noise. Batteries should be replaced every few years, charging bricks about the same. New batteries from Amazon cost about $50. Charging bricks cost $40 from Amazon.
5. Have you ever repasted the CPU and GPU heatsinks? Really helps with not over working the fans.
6. Is there a CD or DVD in the player/recorder? They will spin up every time the laptop is booted.
Please explain further what noise are you writing about.
G752VSK, G75VW-3D, G51J, G1S
Homebuilt Windows Server