use it in pcie 1 and 3 since your running a pcie soundcard if im not wrong?
if the sound card is in a red slot you will disable slot 2b, if its in a black slot ( pcie1x/4x ) the 2b should work.
just be shure you have fastened the cards secure in the pcie slots, power to the molex on the motherboard for extra power to the cards.
manual -> PCIe 3.0/2.0_x8_B2 slot will be disabled when PCIe 3.0/2.0_x16_A2, PCIe 3.0/2.0_
x8_3, PCIe 3.0/2.0_x8_4 slots are occupied <-
PCI Bus Enumeration
this is a sandybridge problem post, but it may have the same affect as on the 4'th gen too.
http://blog.tabinda.net/microhard/the-troubled-sandy-bridge-platform-error-codes-0d-62-94-d2/http://digital.ni.com/public.nsf/allkb/C7234E1FB3B3BAC38625759A007321EBtry and pull out the USB things that you dont use to see if that rules out some thing ( let KB and mouse stay in and pull the other devices )