As anything made from anything gets used after some time, your fans aren't an exclusion. BUT unless you're planning on having this laptop for 20 years you should be fine with turning it on maximum when playing games.
Asus Rog G750JZ
Screen: 1920x1080 17.3'
CPU: Intel® Core™ i7-4700HQ (3.4Ghz @ -70mV)
GPU: GeForce GTX 880M 4GB (OC +125Mhz Core, +600Mhz Memory @ 1.062V)
RAM: Samsung 32GB 1600MHz
Storage #1: Samsung Evo 840 250GB
Storage #2: Samsung Evo 850 500GB
Storage #3: Seagate Barracuda 2TB
Storage #4: Samsung Evo 128GB MicroSD