There are alot of settings to play with in the bios but most you can let on auto.
You can change these settings if you want.
Extreme Tweaking - Enabled
BCLK Recovery - Enabled
DIGI+
Load Line Calibration - medium (4or5)
CPU current capability 140% - 150%
Is your ram stable with XMP enabled? If it is you can let it in XMP mode to do your overclocking or you can run it in manual mode and set your ram manually, the choice is yours.
Set the cpu cache ratio/voltage to auto, you will get the most performance increase by overclocking the cores as far as temps will allow.
Good luck with 4.9GHz, if you have any questions along the way feel free to ask.