Today I spent approx. 3 hours creating a new install of Windows 10 Creators from an ISO and began the process of elimination to find what may be causing the freezing of GPU Tweak.
I installed Windows 10, Intel Chipset and ME drivers, Bluetooth, Wireless, NvME and latest Nvidia drivers. I did not install sound, Corsair drivers for the AIO/keyboard/mouse/power supply. I then installed all Windows Updates.
I then installed the latest GPU Tweak II, rebooted and tested with absolutely no issues with GPU Tweak. I then proceeded to repeat this process with the Creative drivers (as well as Creative Control Panel), Corsair Link 4, Corsair Utility Engine (for mouse and keyboard), Asus Lighting Control for GPU and Asus Lighting Control for Motherboard. No issues with GPU Tweak II.
So at this point I can say with 100% certainty that those programs are not an issue and GPU Tweak works as intended. Something else is conflicting with GPU Tweak.
My next step will be to go through my original Windows install and via task manager to begin comparing running tasks and begin closing them to see which is conflicting with GPU Tweak II.
Going to take a break and enjoy the rest of my Saturday first.
Cheers all.