If you're using a Rampage IV or Maximus V motherboard (or any X79 or Z77 for that matter) along with RAID0 SSDs, you can now get TRIM support by upgrading to the 11.x (currently 11.2) Intel RST drivers.
Anandtech tested the latest driver in a recent article. If you're unsure what TRIM is and why you need it, Anandtech covers that too in the 'Why does TRIM matter?' section.
